Prognostic role of baseline <sup>18</sup> F-FDG pet/CT in squamous cell carcinoma of the paranasal sinuses.
Details
Serval ID
serval:BIB_8DEA11E9608D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Prognostic role of baseline <sup>18</sup> F-FDG pet/CT in squamous cell carcinoma of the paranasal sinuses.
Journal
Head & neck
ISSN
1097-0347 (Electronic)
ISSN-L
1043-3074
Publication state
Published
Issued date
11/2022
Peer-reviewed
Oui
Volume
44
Number
11
Pages
2395-2406
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To retrospectively investigate the prognostic role of baseline <sup>18</sup> F-FDG PET/CT in squamous cell carcinoma (SCC) of the paranasal sinuses.
Clinical features and PET/CT semiquantitative parameters of 49 patients were collected. Anova and Kruskall-Wallis tests were used to assess the relationship between these parameters. Kaplan-Meier, univariate, and multivariate analysis were performed to search for independent prognostic factors for progression free (PFS) and overall survival (OS).
Mean PFS was 29.95 months (SD 29.36) with relapse/progression of disease occurring in 18 patients; mean OS was 33.40 (SD 27.78) months with death occurring in 15 patients. Presence of nodal metastasis (14 subjects) was correlated with standardize uptake value (SUV) max, SUVmean, SUV/blood-pool ratio, SUV/liver ratio, metabolic tumor volume, and total lesion glycolysis. SUVmax, SUVmean, and presence of nodal metastasis resulted as independent prognostic factors for OS.
<sup>18</sup> F-FDG PET/CT semiquantitative parameters confirmed their prognostic role for SCC of paranasal sinuses.
Clinical features and PET/CT semiquantitative parameters of 49 patients were collected. Anova and Kruskall-Wallis tests were used to assess the relationship between these parameters. Kaplan-Meier, univariate, and multivariate analysis were performed to search for independent prognostic factors for progression free (PFS) and overall survival (OS).
Mean PFS was 29.95 months (SD 29.36) with relapse/progression of disease occurring in 18 patients; mean OS was 33.40 (SD 27.78) months with death occurring in 15 patients. Presence of nodal metastasis (14 subjects) was correlated with standardize uptake value (SUV) max, SUVmean, SUV/blood-pool ratio, SUV/liver ratio, metabolic tumor volume, and total lesion glycolysis. SUVmax, SUVmean, and presence of nodal metastasis resulted as independent prognostic factors for OS.
<sup>18</sup> F-FDG PET/CT semiquantitative parameters confirmed their prognostic role for SCC of paranasal sinuses.
Keywords
Carcinoma, Squamous Cell/diagnostic imaging, Carcinoma, Squamous Cell/therapy, Fluorodeoxyglucose F18, Humans, Paranasal Sinuses, Positron Emission Tomography Computed Tomography, Prognosis, Radiopharmaceuticals, Retrospective Studies, Tumor Burden, 18F-FDG, PET/CT, positron emission tomography, sinonasal cancer, squamous cell carcinoma
Pubmed
Web of science
Create date
18/07/2022 9:16
Last modification date
14/06/2023 5:56
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