Gender differences in first episode psychotic mania.

Détails

Ressource 1Télécharger: BIB_8DDA8258DFBC.P001.pdf (204.11 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_8DDA8258DFBC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Gender differences in first episode psychotic mania.
Périodique
Bmc Psychiatry
Auteur(s)
Cotton S.M., Lambert M., Berk M., Schimmelmann B.G., Butselaar F.J., McGorry P.D., Conus P.
ISSN
1471-244X (Electronic)
ISSN-L
1471-244X
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
13
Pages
82
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: epublish
Résumé
BACKGROUND: The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients.
METHODS: Medical file audit assessment of 118 (male = 71; female = 47) patients with FEPM aged 15 to 29 years was undertaken on clinical and functional measures.
RESULTS: Males with FEPM had increased likelihood of substance use (OR = 13.41, p <.001) and forensic issues (OR = 4.71, p = .008), whereas females were more likely to have history of sexual abuse trauma (OR = 7.12, p = .001). At service entry, males were more likely to be using substances, especially cannabis (OR = 2.15, p = .047), had more severe illness (OR = 1.72, p = .037), and poorer functioning (OR = 0.96, p = .045). During treatment males were more likely to decrease substance use (OR = 5.34, p = .008) and were more likely to be living with family (OR = 4.30, p = .009). There were no gender differences in age of onset, psychopathology or functioning at discharge.
CONCLUSIONS: Clinically meaningful gender differences in FEPM were driven by risk factors possibly associated with poor outcome. For males, substance use might be associated with poorer clinical presentation and functioning. In females with FEPM, the impact of sexual trauma on illness course warrants further consideration.
Pubmed
Web of science
Open Access
Oui
Création de la notice
26/03/2013 10:20
Dernière modification de la notice
20/08/2019 15:51
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