Malaria importée: des médicaments toujours plus efficaces et plus sûrs [Imported malaria: safer and more efficacious drugs?].

Détails

ID Serval
serval:BIB_8DA4E882A51A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Malaria importée: des médicaments toujours plus efficaces et plus sûrs [Imported malaria: safer and more efficacious drugs?].
Périodique
Revue Médicale Suisse
Auteur(s)
Genton B., D'Acremont V.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
2013
Volume
9
Numéro
385
Pages
979-984
Langue
français
Notes
Publication types: Case Reports ; English Abstract ; Journal ArticlePublication Status: ppublish
Résumé
In response to the spread of parasite resistance to old antimalarial drugs, the large-scale implementation of artemisinine-based combinations has allowed to improving patient survival and reducing parasite transmission. Even though decreased susceptibility of parasites to artemisinine has been observed in South-East Asia, this phenomenon has no practical implications for travelers with uncomplicated malaria. The combination of artemether-lumefantrine is still very effective and safe, be it for P. falciparum or vivax. Intravenous administration of artesunate has allowed to significantly reducing case fatality rate of severe malaria patients when compared to quinine treatment in endemic areas. Artesunate is also recommended in travelers, but with close monitoring, especially for hematological parameters, in order to confirm its superiority.
Mots-clé
Adult, Antimalarials/therapeutic use, Female, Humans, Malaria/drug therapy, Male, Middle Aged, Travel
Pubmed
Création de la notice
19/09/2013 21:15
Dernière modification de la notice
03/03/2018 19:16
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