EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritis

Détails

ID Serval
serval:BIB_8D6258BA03FA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritis
Périodique
Annals of the Rheumatic Diseases
Auteur(s)
D'Agostino  M. A., Conaghan  P., Le Bars  M., Baron  G., Grassi  W., Martin-Mola  E., Wakefield  R., Brasseur  J. L., So  A., Backhaus  M., Malaise  M., Burmester  G., Schmidely  N., Ravaud  P., Dougados  M., Emery  P.
ISSN
0003-4967 (Print)
Statut éditorial
Publié
Date de publication
12/2005
Volume
64
Numéro
12
Pages
1703-9
Notes
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't --- Old month value: Dec
Résumé
OBJECTIVES: To assess the prevalence of inflammation in subjects with chronic painful knee osteoarthritis (OA), as determined by the presence of synovitis or joint effusion at ultrasonography (US); and to evaluate the correlation between synovitis, effusion, and clinical parameters. METHODS: A cross sectional, multicentre, European study was conducted under the umbrella of EULAR-ESCISIT. SUBJECTS: had primary chronic knee OA (ACR criteria) with pain during physical activity >or=30 mm for at least 48 hours. Clinical parameters were collected by a rheumatologist and an US examination of the painful knee was performed by a radiologist or rheumatologist within 72 hours of the clinical examination. Ultrasonographic synovitis was defined as synovial thickness >or=4 mm and diffuse or nodular appearance, and a joint effusion was defined as effusion depth >or=4 mm. RESULTS: 600 patients with painful knee OA were analysed. At US 16 (2.7%) had synovitis alone, 85 (14.2%) had both synovitis and effusion, 177 (29.5%) had joint effusion alone, and 322 (53.7%) had no inflammation according to the definitions employed. Multivariate analysis showed that inflammation seen by US correlated statistically with advanced radiographic disease (Kellgren-Lawrence grade >or=3; odds ratio (OR)=2.20 and 1.91 for synovitis and joint effusion, respectively), and with clinical signs and symptoms suggestive of an inflammatory "flare", such as joint effusion on clinical examination (OR=1.97 and 2.70 for synovitis and joint effusion, respectively) or sudden aggravation of knee pain (OR=1.77 for joint effusion). CONCLUSION: US can detect synovial inflammation and effusion in painful knee OA, which correlate significantly with knee synovitis, effusion, and clinical parameters suggestive of an inflammatory "flare".
Mots-clé
Aged Cross-Sectional Studies Europe/epidemiology Exudates and Transudates/ultrasonography Female Humans Knee Joint/ultrasonography Male Middle Aged Multivariate Analysis Osteoarthritis, Knee/*epidemiology/ultrasonography Pain Measurement Prevalence Severity of Illness Index Synovitis/epidemiology/ultrasonography
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 9:38
Dernière modification de la notice
08/05/2019 21:49
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