Work precarity, referring to the work-related psychological state of insecurity, instability, and powerlessness, is on the rise. Despite being employed, workers are increasingly exposed to work precarity due to the global disparities of access to decent work. Paid domestic cleaning (PDC) workers represent a vulnerable group, exposed to adverse employment conditions and limited labor rights and protections. Yet, the working conditions in PDC have not been studied in the light of precariousness and precarity. Drawing from the work precarity framework (WPF), the present study utilizes semi-structured interviews with 24 PDC workers in Switzerland to investigate if and how they experienced work precarity in the face of adverse working conditions, and to what extent they could access protective resources against such precarity. Experiences of precarity stemmed from insufficient and insecure income, lack of labor protections and rights, lack of social recognition, and unsafe physical and psychological working conditions. Participants reported negative work-related outcomes in terms of health impairment, social stigmatization, and am- bivalent attitudes towards their job. Moreover, protective personal, social, and institutional resources were identified as limited or inconsistent. Among the study’s contributions, we highlight precarity-derived challenges vulnerabilized workers face. Implications for research, policy, and practice will be discussed.