Direct measurement of three-dimensionally reconstructed flow convergence surface area and regurgitant flow in aortic regurgitation: in vitro and chronic animal model studies
Details
Serval ID
serval:BIB_8D031AAD3A59
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Direct measurement of three-dimensionally reconstructed flow convergence surface area and regurgitant flow in aortic regurgitation: in vitro and chronic animal model studies
Journal
Circulation
ISSN
0009-7322 (Print)
Publication state
Published
Issued date
11/1997
Volume
96
Number
10
Pages
3687-95
Notes
In Vitro
Journal Article
Research Support, U.S. Gov't, P.H.S. --- Old month value: Nov 18
Journal Article
Research Support, U.S. Gov't, P.H.S. --- Old month value: Nov 18
Abstract
BACKGROUND: Evaluation of flow convergence (FC) with two-dimensional (2D) imaging systems may not be sufficiently accurate to characterize these often asymmetric, complex phenomena. The aim of this study was to validate a three-dimensional (3D) method for determining the severity of aortic regurgitation (AR) in an experimental animal model. METHODS AND RESULTS: In six sheep with surgically induced chronic AR, 20 hemodynamically different states were studied. Instantaneous regurgitant flow rates were obtained by aortic and pulmonary electromagnetic flow meters. Video composite data of color Doppler flow mapping images were transferred into a TomTec computer after computer-controlled 180 degrees rotational acquisition. Direct measurement of the 3D reconstructed FC surface areas as well as measurements of FC areas estimated with 2D methods with hemispherical and hemielliptical assumptions were performed, and values were multiplied by the aliasing velocity to obtain peak regurgitant flow rates. There was better agreement between 3D and electromagnetically derived flow rates than there was between the 2D and the reference values (r=.94, y=1.0x-0.16, difference=0.02 L/min for the 3D method; r=.80, y=1.6x-0.3, difference=1.2 L/min for the 2D hemispherical method; r=.75, y=0.90x+0.2, difference=-0.20 L/min for the 2D hemielliptical method). CONCLUSIONS: Without any geometrical assumption, the 3D method provided better delineation of the FC zones and direct measurements of FC surface areas, permitting more accurate quantification of the severity of AR than the 2D methods.
Keywords
Animals
Aorta/physiopathology
Aortic Valve Insufficiency/*physiopathology/*ultrasonography
Chronic Disease
*Echocardiography
Electrocardiography
Electromagnetics/instrumentation/methods
Feasibility Studies
Hemodynamic Processes/physiology
*Image Processing, Computer-Assisted
Observer Variation
Pulmonary Artery/physiopathology
Regional Blood Flow
Rheology
Sheep
Ultrasonography, Doppler, Color
Pubmed
Web of science
Create date
28/01/2008 9:47
Last modification date
20/08/2019 14:51