Inflammation, immunity, and vaccines for Helicobacter pylori infection.

Détails

ID Serval
serval:BIB_8BC055D1BBD0
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Inflammation, immunity, and vaccines for Helicobacter pylori infection.
Périodique
Helicobacter
Auteur(s)
Velin D., Straubinger K., Gerhard M.
ISSN
1523-5378 (Electronic)
ISSN-L
1083-4389
Statut éditorial
Publié
Date de publication
09/2016
Peer-reviewed
Oui
Volume
21 Suppl 1
Pages
26-29
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The tight control of the innate and adaptive immune responses in the stomach mucosa during chronic Helicobacter pylori infection is of prime importance for the bacteria to persist and for the host to prevent inflammation-driven diseases. This review summarizes recent data on the roles of innate and adaptive immune responses during H. pylori/host interactions. In addition, the latest preclinical developments of H. pylori vaccines are discussed with a special focus on the clinical trial reported by Zeng et al., who provided evidence that oral vaccination significantly reduces the acquisition of natural H. pylori infection in children.

Mots-clé
Bacterial Vaccines/administration & dosage, Bacterial Vaccines/immunology, Bacterial Vaccines/isolation & purification, Helicobacter Infections/immunology, Helicobacter Infections/pathology, Helicobacter Infections/prevention & control, Helicobacter pylori/immunology, Host-Pathogen Interactions, Humans, Inflammation/pathology, Inflammation/prevention & control, Randomized Controlled Trials as Topic
Pubmed
Création de la notice
15/09/2016 20:29
Dernière modification de la notice
03/03/2018 19:12
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