A randomised controlled trial of the pectoral nerves-2 (PECS-2) block for radical mastectomy.

Détails

ID Serval
serval:BIB_8B4FBCFCD10B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
A randomised controlled trial of the pectoral nerves-2 (PECS-2) block for radical mastectomy.
Périodique
Anaesthesia
Auteur(s)
Al Ja'bari A., Robertson M., El-Boghdadly K., Albrecht E.
ISSN
1365-2044 (Electronic)
ISSN-L
0003-2409
Statut éditorial
Publié
Date de publication
10/2019
Peer-reviewed
Oui
Volume
74
Numéro
10
Pages
1277-1281
Langue
anglais
Notes
Publication types: Journal Article ; Randomized Controlled Trial
Publication Status: ppublish
Résumé
We randomly allocated 50 women scheduled for radical mastectomy to pectoral nerves-2 (PECS-2) block (n = 25) or no block (n = 25), 20 and 22 of whom we analysed for the primary outcome of a cumulative 24-h postoperative morphine dose. We gave intra-operative sufentanil, magnesium, dexamethasone and droperidol. Participants received regular postoperative paracetamol, ibuprofen and patient-controlled intravenous morphine. Pectoral nerves-2 block reduced mean (SD) cumulative 24 h postoperative morphine dose from 9.7 (8.9) mg to 5.0 (5.4) mg and 48 h morphine dose from 12.8 (12.5) mg to 6.0 (6.5) mg, p = 0.04 for both. The mean (SD) pain scores 24 h and 48 h after surgery were similar with or without block: 0.8 (1.4) vs. 1.2 (1.9), p = 0.39; and 0.2 (0.4) vs. 0.9 (1.8), p = 0.09, respectively. Rates of postoperative nausea, vomiting and pruritus were unaffected. Rates of chronic pain at six postoperative months were 2/19 and 2/18 after block and no block, respectively, p = 0.95.
Mots-clé
Aged, Analgesics, Opioid/administration & dosage, Analgesics, Opioid/therapeutic use, Breast Neoplasms/surgery, Female, Humans, Mastectomy, Radical/methods, Middle Aged, Morphine/administration & dosage, Morphine/therapeutic use, Nerve Block, Pain Measurement, Pain, Postoperative/drug therapy, Pain, Postoperative/epidemiology, Postoperative Nausea and Vomiting/epidemiology, Prospective Studies, Pruritus/chemically induced, Pruritus/epidemiology, Thoracic Nerves, Treatment Outcome, analgesia, mastectomy, peripheral nerve block, postoperative pain
Pubmed
Web of science
Création de la notice
21/07/2019 17:10
Dernière modification de la notice
08/10/2019 6:09
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