Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.

Détails

Ressource 1Télécharger: BIB_8AEAA8429053.P001.pdf (135.25 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_8AEAA8429053
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.
Périodique
Environmental Health Perspectives
Auteur(s)
Coecke S., Goldberg A.M., Allen S., Buzanska L., Calamandrei G., Crofton K., Hareng L., Hartung T., Knaut H., Honegger P., Jacobs M., Lein P., Li A., Mundy W., Owen D., Schneider S., Silbergeld E., Reum T., Trnovec T., Monnet-Tschudi F., Bal-Price A.
ISSN
0091-6765 (Print)
ISSN-L
0091-6765
Statut éditorial
Publié
Date de publication
06/2007
Volume
115
Numéro
6
Pages
924-931
Langue
anglais
Notes
Publication types: In Vitro ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
This is the report of the first workshop on Incorporating In Vitro Alternative Methods for Developmental Neurotoxicity (DNT) Testing into International Hazard and Risk Assessment Strategies, held in Ispra, Italy, on 19-21 April 2005. The workshop was hosted by the European Centre for the Validation of Alternative Methods (ECVAM) and jointly organized by ECVAM, the European Chemical Industry Council, and the Johns Hopkins University Center for Alternatives to Animal Testing. The primary aim of the workshop was to identify and catalog potential methods that could be used to assess how data from in vitro alternative methods could help to predict and identify DNT hazards. Working groups focused on two different aspects: a) details on the science available in the field of DNT, including discussions on the models available to capture the critical DNT mechanisms and processes, and b) policy and strategy aspects to assess the integration of alternative methods in a regulatory framework. This report summarizes these discussions and details the recommendations and priorities for future work.
Mots-clé
Animal Testing Alternatives/legislation & jurisprudence, Animal Testing Alternatives/standards, Animals, Humans, Models, Biological, Nervous System/drug effects, Nervous System/embryology, Toxicity Tests/methods, Validation Studies as Topic, Xenobiotics/toxicity
Pubmed
Web of science
Création de la notice
24/01/2008 14:11
Dernière modification de la notice
03/03/2018 19:10
Données d'usage