Platelet count at term pregnancy: a reappraisal of the threshold

Détails

ID Serval
serval:BIB_8A55446D7D41
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Platelet count at term pregnancy: a reappraisal of the threshold
Périodique
Obstetrics and Gynecology
Auteur(s)
Boehlen  F., Hohlfeld  P., Extermann  P., Perneger  T. V., de Moerloose  P.
ISSN
0029-7844 (Print)
Statut éditorial
Publié
Date de publication
01/2000
Volume
95
Numéro
1
Pages
29-33
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan
Résumé
OBJECTIVE: To assess the safety of a new platelet count threshold for the definition of maternal thrombocytopenia late in pregnancy. METHODS: A platelet count was performed in 6770 pregnant women late in pregnancy and in 6103 of their newborns as well as in a control group of 287 age-matched nonpregnant healthy women. RESULTS: The prevalence of maternal thrombocytopenia (platelet count less than 150 x 10(9)/L) was 11.6%. The mean platelet counts (248 compared with 213 x 10(9)/L) and 2.5th percentile (164 compared with 116 x 10(9)/L) were significantly higher in healthy nonpregnant women than in pregnant women. Among thrombocytopenic pregnant women, 621 (79%) had platelet counts between 116 and 149 x 10(9)/L; none (0%; 95% confidence interval 0, 0.6) had complications related to thrombocytopenia, and none of their newborns had severe thrombocytopenia (platelet count less than 20 x 10(9)/L). CONCLUSION: In healthy pregnant women, a platelet count over 115 x 10(9)/L late in pregnancy does not require further investigation during pregnancy and may be considered a safe threshold.
Mots-clé
Adolescent Adult Female Humans Middle Aged *Platelet Count Pregnancy/*physiology Pregnancy Complications, Hematologic/*diagnosis Reference Values Thrombocytopenia/*diagnosis
Pubmed
Web of science
Création de la notice
25/01/2008 12:12
Dernière modification de la notice
03/03/2018 19:09
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