Verb and noun generation tasks in Huntington's disease.

Détails

ID Serval
serval:BIB_87A5AB4CB7F3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Verb and noun generation tasks in Huntington's disease.
Périodique
Movement Disorders
Auteur(s)
Péran P., Démonet J.F., Pernet C., Cardebat D.
ISSN
0885-3185 (Print)
ISSN-L
0885-3185
Statut éditorial
Publié
Date de publication
2004
Peer-reviewed
Oui
Volume
19
Numéro
5
Pages
565-571
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish. PDF type: Brief Report
Résumé
We compared noun- and verb-generation tasks in a demented group (n = 9, Dementia Rating Scale < or = 129) and in a non-demented group (n = 17, Dementia Rating Scale > 129) of Huntington's disease (HD) patients compared to 26 matched normal subjects. We did not find a specific deficit for verb production in non-demented patients who had a performance similar to but weaker than that of the controls across the four tasks. The profile of results was different in the demented group because, apart from a global deficit whatever the task in comparison with both non-demented and control groups, the demented patients exhibited increased difficulties in the two tasks implying verb production. The deficit of verb production observed in demented HD patients is discussed in relation to the damage to the motor loop in HD patients at later stages of disease.
Mots-clé
Aphasia, Broca/diagnosis, Aphasia, Broca/etiology, Cognition Disorders/diagnosis, Cognition Disorders/etiology, Female, Frontal Lobe/physiopathology, Humans, Huntington Disease/complications, Huntington Disease/genetics, Male, Middle Aged, Nerve Tissue Proteins, Neuropsychological Tests, Nuclear Proteins, Proteins/genetics, Severity of Illness Index, Temporal Lobe/physiopathology, Vocabulary
Pubmed
Web of science
Création de la notice
24/03/2013 19:40
Dernière modification de la notice
03/03/2018 19:02
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