Astrocytes: Orchestrating synaptic plasticity?

Détails

Ressource 1Télécharger: BIB_87447CE928BD.P001.pdf (1977.81 [Ko])
Etat: Serval
Version: Author's accepted manuscript
ID Serval
serval:BIB_87447CE928BD
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Astrocytes: Orchestrating synaptic plasticity?
Périodique
Neuroscience
Auteur(s)
De Pittà M., Brunel N., Volterra A.
ISSN
1873-7544 (Electronic)
ISSN-L
0306-4522
Statut éditorial
Publié
Date de publication
04/2016
Peer-reviewed
Oui
Volume
323
Pages
43-61
Langue
anglais
Résumé
Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the elucidation of its constituting mechanisms is of crucial importance in many aspects of normal and pathological brain function. In particular, a prominent aspect that remains debated is how the plasticity mechanisms, that encompass a broad spectrum of temporal and spatial scales, come to play together in a concerted fashion. Here we review and discuss evidence that pinpoints to a possible non-neuronal, glial candidate for such orchestration: the regulation of synaptic plasticity by astrocytes.
Pubmed
Web of science
Création de la notice
22/01/2016 18:21
Dernière modification de la notice
03/03/2018 19:01
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