A double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T

Détails

ID Serval
serval:BIB_8737C8ADD1A1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
A double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T
Périodique
Magnetic Resonance in Medicine
Auteur(s)
Roig Eulalia Serès, Magill Arthur W., Donati Guillaume, Meyerspeer Martin, Xin Lijing, Ipek Ozlem, Gruetter Rolf
ISSN
1522-2594
Statut éditorial
Publié
Date de publication
02/2015
Peer-reviewed
Oui
Volume
73
Numéro
2
Pages
894-900
Langue
anglais
Résumé
Purpose Carbon-13 magnetic resonance spectroscopy (13C-MRS) is challenging because of the inherent low sensitivity of 13C detection and the need for radiofrequency transmission at the 1H frequency while receiving the 13C signal, the latter requiring electrical decoupling of the 13C and 1H radiofrequency channels. In this study, we added traps to the 13C coil to construct a quadrature-13C/quadrature-1H surface coil, with sufficient isolation between channels to allow simultaneous operation at both frequencies without compromise in coil performance. Methods Isolation between channels was evaluated on the bench by measuring all coupling parameters. The quadrature mode of the quadrature-13C coil was assessed using in vitro 23Na gradient echo images. The signal-to-noise ratio (SNR) was measured on the glycogen and glucose resonances by 13C-MRS in vitro, compared with that obtained with a linear-13C/quadrature-1H coil, and validated by 13C-MRS in vivo in the human calf at 7T. Results Isolation between channels was better than â^'30 dB. The 23Na gradient echo images indicate a region where the field is strongly circularly polarized. The quadrature coil provided an SNR enhancement over a linear coil of 1.4, in vitro and in vivo. Conclusion It is feasible to construct a double-quadrature 13C-1H surface coil for proton decoupled sensitivity enhanced 13C-NMR spectroscopy in humans at 7T. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc.
Mots-clé
RF coils, double-quadrature, trap, 13C-MRS, glycogen, human calf
Pubmed
Web of science
Création de la notice
04/03/2014 10:56
Dernière modification de la notice
03/03/2018 19:01
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