Cluster of oral atypical Candida albicans isolates in a group of human immunodeficiency virus-positive drug users

Details

Serval ID
serval:BIB_870B904144C9
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cluster of oral atypical Candida albicans isolates in a group of human immunodeficiency virus-positive drug users
Journal
Journal of Clinical Microbiology
Author(s)
Boerlin  P., Boerlin-Petzold  F., Durussel  C., Addo  M., Pagani  J. L., Chave  J. P., Bille  J.
ISSN
0095-1137
Publication state
Published
Issued date
05/1995
Peer-reviewed
Oui
Volume
33
Number
5
Pages
1129-35
Notes
Journal Article --- Old month value: May
Abstract
Twenty-one chlamydospore-forming and germ tube-positive Candida albicans clinical isolates from 15 human immunodeficiency virus (HIV)-positive and 3 HIV-negative patients were examined by two different genetic methods. Multilocus enzyme electrophoresis and hybridization with the C. albicans-specific Ca3 probe showed that such isolates can be split into two genetically distinct groups that can be clearly distinguished. One group mainly contained strains with atypical sugar assimilation patterns and could be distinguished from the other group by the absence of intracellular beta-glucosidase activity. All 13 strains belonging to this group were isolated from the oral cavities of asymptomatic HIV-positive drug users and may be less pathogenic than the eight strains from the other group isolated either from HIV-positive patients with oropharyngeal candidiasis or from HIV-negative patients with invasive candidiasis.
Keywords
AIDS-Related Opportunistic Infections/complications/diagnosis/*microbiology Candida albicans/classification/genetics/*isolation & purification Candidiasis, Oral/*complications/diagnosis/*microbiology Cluster Analysis Enzymes/metabolism Genotype Humans Phenotype Substance Abuse, Intravenous/complications/*microbiology beta-Glucosidase/metabolism
Pubmed
Web of science
Create date
11/02/2008 12:40
Last modification date
20/08/2019 14:46
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