Flow driven robotic navigation of microengineered endovascular probes.

Details

Serval ID
serval:BIB_85D24EEB24A5
Type
Article: article from journal or magazin.
Collection
Publications
Title
Flow driven robotic navigation of microengineered endovascular probes.
Journal
Nature communications
Author(s)
Pancaldi L., Dirix P., Fanelli A., Lima A.M., Stergiopulos N., Mosimann P.J., Ghezzi D., Sakar M.S.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Publication state
Published
Issued date
22/12/2020
Peer-reviewed
Oui
Volume
11
Number
1
Pages
6356
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
Minimally invasive medical procedures, such as endovascular catheterization, have considerably reduced procedure time and associated complications. However, many regions inside the body, such as in the brain vasculature, still remain inaccessible due to the lack of appropriate guidance technologies. Here, experimentally and through numerical simulations, we show that tethered ultra-flexible endovascular microscopic probes can be transported through tortuous vascular networks with minimal external intervention by harnessing hydrokinetic energy. Dynamic steering at bifurcations is performed by deformation of the probe head using magnetic actuation. We developed an endovascular microrobotic toolkit with a cross-sectional area that is orders of magnitude smaller than the smallest catheter currently available. Our technology has the potential to improve state-of-the-art practices as it enhances the reachability, reduces the risk of iatrogenic damage, significantly increases the speed of robot-assisted interventions, and enables the deployment of multiple leads simultaneously through a standard needle injection and saline perfusion.
Keywords
Animals, Catheters, Computer Simulation, Ear/blood supply, Ear/surgery, Endovascular Procedures/instrumentation, Equipment Design, Humans, Magnetic Phenomena, Microfluidics, Phantoms, Imaging, Rabbits, Rheology, Robotics, Temperature, Translational Research, Biomedical
Pubmed
Web of science
Open Access
Yes
Create date
21/03/2024 12:00
Last modification date
22/03/2024 8:25
Usage data