Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.

Détails

ID Serval
serval:BIB_84ABF5986D70
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.
Périodique
Science
Auteur(s)
Neafsey D.E., Waterhouse R.M., Abai M.R., Aganezov S.S., Alekseyev M.A., Allen J.E., Amon J., Arcà B., Arensburger P., Artemov G., Assour L.A., Basseri H., Berlin A., Birren B.W., Blandin S.A., Brockman A.I., Burkot T.R., Burt A., Chan C.S., Chauve C., Chiu J.C., Christensen M., Costantini C., Davidson V.L., Deligianni E., Dottorini T., Dritsou V., Gabriel S.B., Guelbeogo W.M., Hall A.B., Han M.V., Hlaing T., Hughes D.S., Jenkins A.M., Jiang X., Jungreis I., Kakani E.G., Kamali M., Kemppainen P., Kennedy R.C., Kirmitzoglou I.K., Koekemoer L.L., Laban N., Langridge N., Lawniczak M.K., Lirakis M., Lobo N.F., Lowy E., MacCallum R.M., Mao C., Maslen G., Mbogo C., McCarthy J., Michel K., Mitchell S.N., Moore W., Murphy K.A., Naumenko A.N., Nolan T., Novoa E.M., O'Loughlin S., Oringanje C., Oshaghi M.A., Pakpour N., Papathanos P.A., Peery A.N., Povelones M., Prakash A., Price D.P., Rajaraman A., Reimer L.J., Rinker D.C., Rokas A., Russell T.L., Sagnon N., Sharakhova M.V., Shea T., Simão F.A., Simard F., Slotman M.A., Somboon P., Stegniy V., Struchiner C.J., Thomas G.W., Tojo M., Topalis P., Tubio J.M., Unger M.F., Vontas J., Walton C., Wilding C.S., Willis J.H., Wu Y.C., Yan G., Zdobnov E.M., Zhou X., Catteruccia F., Christophides G.K., Collins F.H., Cornman R.S., Crisanti A., Donnelly M.J., Emrich S.J., Fontaine M.C., Gelbart W., Hahn M.W., Hansen I.A., Howell P.I., Kafatos F.C., Kellis M., Lawson D., Louis C., Luckhart S., Muskavitch M.A., Ribeiro J.M., Riehle M.A., Sharakhov I.V., Tu Z., Zwiebel L.J., Besansky N.J.
ISSN
1095-9203 (Electronic)
ISSN-L
0036-8075
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
347
Numéro
6217
Pages
1258522
Langue
anglais
Résumé
Variation in vectorial capacity for human malaria among Anopheles mosquito species is determined by many factors, including behavior, immunity, and life history. To investigate the genomic basis of vectorial capacity and explore new avenues for vector control, we sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution. Comparative analyses show faster rates of gene gain and loss, elevated gene shuffling on the X chromosome, and more intron losses, relative to Drosophila. Some determinants of vectorial capacity, such as chemosensory genes, do not show elevated turnover but instead diversify through protein-sequence changes. This dynamism of anopheline genes and genomes may contribute to their flexible capacity to take advantage of new ecological niches, including adapting to humans as primary hosts.

Mots-clé
Animals, Anopheles/classification, Anopheles/genetics, Base Sequence, Chromosomes, Insect/genetics, Drosophila/genetics, Evolution, Molecular, Genome, Insect, Humans, Insect Vectors/classification, Insect Vectors/genetics, Malaria/transmission, Molecular Sequence Data, Phylogeny, Sequence Alignment
Pubmed
Web of science
Open Access
Oui
Création de la notice
20/09/2017 10:52
Dernière modification de la notice
08/05/2019 21:20
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