Arabidopsis  SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity

Détails

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Etat: Serval
Version: Final published version
ID Serval
serval:BIB_84A51323B2E3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Arabidopsis  SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity
Périodique
Nature Communications
Auteur(s)
Pietra S., Gustavsson A., Kiefer C., Kalmbach L., Hörstedt P., Ikeda Y., Stepanova A.N., Alonso J.M., Grebe M.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
4
Pages
2779
Langue
anglais
Notes
Publication types: Article ; research-article Identifiant PubMed Central: PMC3868209
Résumé
The orientation of cell division and the coordination of cell polarity within the plane of the tissue layer (planar polarity) contribute to shape diverse multicellular organisms. The root of Arabidopsis thaliana displays regularly oriented cell divisions, cell elongation and planar polarity providing a plant model system to study these processes. Here we report that the SABRE protein, which shares similarity with proteins of unknown function throughout eukaryotes, has important roles in orienting cell division and planar polarity. SABRE localizes at the plasma membrane, endomembranes, mitotic spindle and cell plate. SABRE stabilizes the orientation of CLASP-labelled preprophase band microtubules predicting the cell division plane, and of cortical microtubules driving cell elongation. During planar polarity establishment, sabre is epistatic to clasp at directing polar membrane domains of Rho-of-plant GTPases. Our findings mechanistically link SABRE to CLASP-dependent microtubule organization, shedding new light on the function of SABRE-related proteins in eukaryotes.
Mots-clé
Arabidopsis/cytology, Arabidopsis/physiology, Arabidopsis Proteins/genetics, Arabidopsis Proteins/metabolism, Cell Division/physiology, Cell Polarity/physiology, Gene Expression Regulation, Plant/physiology, Intracellular Signaling Peptides and Proteins/genetics, Intracellular Signaling Peptides and Proteins/metabolism, Microtubule-Associated Proteins/genetics, Microtubule-Associated Proteins/metabolism
Pubmed
Web of science
Open Access
Oui
Création de la notice
11/07/2016 11:04
Dernière modification de la notice
08/05/2019 21:20
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