Reproducibility of retinal thickness measurements in normal eyes using optical coherence tomography.

Details

Serval ID
serval:BIB_8459
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Reproducibility of retinal thickness measurements in normal eyes using optical coherence tomography.
Journal
Ophthalmic Surgery and Lasers
Author(s)
Baumann M., Gentile R.C., Liebmann J.M., Ritch R.
ISSN
1082-3069
Publication state
Published
Issued date
1998
Volume
29
Number
4
Pages
280-285
Language
english
Abstract
BACKGROUND AND OBJECTIVE: To determine the reproducibility of retinal thickness measurements in normal eyes using optical coherence tomography (OCT). PATIENTS AND METHODS: Multiple 3.20-mm vertical cross-sectional images through the center of fixation of consecutive patients with normal results on ocular examinations were obtained. Each image was divided into seven 320-micron segments. Regional retinal thicknesses for each section were measured using both the manually assisted (requiring observer localization of reflectivity peaks) and the automated modes (observer-independent measurement) of the computer software. RESULTS: Eighteen right eyes were studied. The mean coefficient of variation was less than 10% for all locations using the manually assisted method (average standard deviation less than 17 microns [range 9 to 16 microns]). The automated method was less reliable, with a coefficient of variation greater than 10% for locations within 500 microns of fixation. Automated measurements at fixation were the least reproducible because of poor internal limiting membrane reflectivity. CONCLUSION: OCT is capable of reproducible measurement of retinal thickness in normal eyes. Computer-driven, automated measurement of retinal thickness within 500 microns of fixation needs to be refined and its reproducibility reassessed in this region.
Keywords
Adult, Female, Humans, Image Processing, Computer-Assisted, Male, Observer Variation, Reference Values, Reproducibility of Results, Retina/anatomy &amp, histology, Tomography/methods
Pubmed
Web of science
Create date
19/11/2007 12:46
Last modification date
20/08/2019 14:44
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