Assessment of Cannabis Acute Effects on Driving Skills: Laboratory, Simulator, and On-Road Studies

Détails

ID Serval
serval:BIB_841EA21B373A
Type
Partie de livre
Sous-type
Chapitre: chapitre ou section
Collection
Publications
Titre
Assessment of Cannabis Acute Effects on Driving Skills: Laboratory, Simulator, and On-Road Studies
Titre du livre
Handbook of Cannabis and Related Pathologies
Auteur(s)
Bondallaz P., Chtioui H., Favrat B., Fornari E., Giroud C., Maeder P.
Editeur
Elsevier BV
ISBN
9780128007563
Statut éditorial
Publié
Date de publication
2017
Numéro de chapitre
39
Pages
379-390
Langue
anglais
Résumé
The vast majority of epidemiological studies indicate that cannabinoids constitute the most frequently encountered psychoactive substances in the blood of drivers who are drug-impaired and/or involved in accidents, and thus cannabis must be considered a serious problem for traffic safety. In order to better understand its effects on cognitive functions involved in the short-term ability to drive, experimental research has been conducted based on laboratory, simulator, or on-road studies and, more recently, brain imaging. According to the results reviewed in the present chapter, cannabis use has been shown to impair actual driving performance by increasing lane weaving and mean headway. It also impairs cognitive functions, including working memory, motor inhibition, and divided attention. However, several factors, including history of cannabis use, routes of administration and dose ranges, as well as study designs (eg, treatment blinding), explain some discrepancies. Moreover, the neurobiological mechanisms underlying the effects of cannabis on safe driving remain poorly understood, as does the correlation between body fluids (blood, oral fluid) concentrations and psychoactive effects of THC and its main active metabolites.
Mots-clé
THC, cannabis, psychomotor effects, fitness to drive, driving
Web of science
Création de la notice
07/02/2017 8:45
Dernière modification de la notice
20/08/2019 14:43
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