De novo undifferentiated pleomorphic sarcoma arising from a renal allograft: A case report

Détails

Ressource 1Télécharger: doi10.1016j.ctrc.2015.01.002.pdf (4416.62 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_830FB88233B9
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
De novo undifferentiated pleomorphic sarcoma arising from a renal allograft: A case report
Périodique
Cancer Treatment Communications
Auteur(s)
Mayor G., Wirth GJ, Sanchez A., La Harpe R., Gehrig C., Iselin C.
ISSN
2213-0896
ISSN-L
2213-0896
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
3
Pages
17-20
Langue
anglais
Résumé
To the best of our knowledge, this is the first report of an undifferentiated pleomorphic sarcoma arising from a renal graft. Transplantectomy was performed in a 47-year old woman presenting to the emergency room because of general weakness. Preoperative workup revealed a 5.5 cm malignant mass of the graft which was not present on routine ultrasound performed 12 months earlier. Following transplantectomy, local recurrence developed despite complete tumor resection and interruption of immunosuppression. Despite radiation therapy, the outcome was ultimately fatal. Genetic analysis revealed that the tumor had arisen from donor tissue. Annual ultrasound surveillance might not be enough effective to screen for these rare high grade neoplasms.
Mots-clé
Renal graft cancer, Pleomorphic sarcoma, Kidney transplantation, Post-transplant malignancy
Open Access
Oui
Création de la notice
15/04/2016 10:50
Dernière modification de la notice
08/05/2019 21:15
Données d'usage