Does spontaneous remission occur in polyarteritis nodosa?
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Détails

ID Serval
serval:BIB_82F2D50E0F01
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Does spontaneous remission occur in polyarteritis nodosa?
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Périodique
Clinical nephrology
Auteur(s)
Beyaert S., Pruijm M., Qanadli S.D., Vollenweider P., Halfon M.
ISSN
0301-0430 (Print)
ISSN-L
0301-0430
Statut éditorial
Publié
Date de publication
05/2017
Peer-reviewed
Oui
Volume
87 (2017)
Numéro
5
Pages
255-260
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Polyarteritis nodosa (PAN) is a systemic vasculitis involving mainly medium-sized arteries and, rarely, small-sized arteries. The diagnosis is principally based on clinical exams, biopsy of an affected organ, and/or arteriography of renal or mesenteric arteries. Once diagnosed, immunosuppressive agents, such as glucocorticoids and cyclophosphamide, are generally introduced as soon as possible. Whether spontaneous remission of PAN occurs is therefore largely unknown.
We describe the case of a 51-year-old woman who presented with a 4-day-history of intense pain in her left flank, hypertension, fever, microscopic hematuria, and acute renal failure. Contrast-enhanced renal ultrasound strongly suggested bilateral renal infarction. Medical history and an extensive workup allowed to exclude systemic embolism, recreational drug abuse, cardiac arrhythmias, and thrombophilia. A possible diagnosis of PAN was considered; however, within 2 weeks of admission, spontaneous remission of her clinical and biological symptoms occurred without the use of any immunosuppressive treatment. Finally, 3 months later, renal arteriography confirmed the diagnosis of PAN. The patient remains free of symptoms 1 year after initial presentation.
This case illustrates the importance of considering PAN in the differential diagnosis of renal infarction with inflammatory syndrome and shows that spontaneous remission of renal PAN can occur.
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Pubmed
Web of science
Création de la notice
23/02/2017 16:38
Dernière modification de la notice
20/08/2019 15:42
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