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Subversion of host immune responses by viral superantigens.
Trends in Microbiology
Recent experiments with mouse mammary tumor virus indicate that expression of a virally encoded superantigen by B cells and its subsequent recognition by T cells are essential steps for amplification of infection and virus transmission. Preliminary results suggest that superantigens may also be expressed during retroviral infection in humans.
Animals, Antigens, Viral/immunology, Humans, Immune System/immunology, Lymphocytes/microbiology, Mammary Tumor Virus, Mouse/immunology, Mice, Retroviridae Infections/immunology, Superantigens/immunology, Tumor Virus Infections/immunology
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