Brucellose: presentation clinique variee chez 9 patients. [Brucellosis: a varied clinical presentation in 9 patients]

Détails

ID Serval
serval:BIB_824933DE53A6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Brucellose: presentation clinique variee chez 9 patients. [Brucellosis: a varied clinical presentation in 9 patients]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur(s)
Vogt  P., Francioli  P., Bille  J., Glauser  M. P.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
12/1984
Volume
114
Numéro
51
Pages
1906-9
Notes
English Abstract
Journal Article --- Old month value: Dec 22
Résumé
From 1973 to 1983 nine cases of Brucella melitensis infection were hospitalised at the Centre hospitalier universitaire vaudois (CHUV), Lausanne. In each case, the infection was acquired in a Mediterranean country (4 cases in Italy, 2 in Spain, 2 in Portugal and 1 in Greece). In 6 of the cases the disease was acquired by ingestion of dairy products and in 2 cases by direct animal contact. Despite classical initial symptomatology (fever, rigors, weakness), the time from first symptoms to diagnosis varied between 10 days and 5 months. This delay probably explains why 6 of 9 patients were admitted because of septic complications: orchi-epididymitis, arthritis, meningitis and endocarditis. With prolonged antibiotherapy, the evolution was favourable in all cases. The patient who presented with endocarditis required emergency aortic valve replacement. Culture of the valve showed the presence of 10(9) B. melitensis/g of tissue. Cure was achieved by the administration of streptomycin and tetracycline for 6 weeks, followed by cotrimoxazole for one year. These cases show that the diagnosis of Brucella infection is becoming rare in Switzerland. It is often not suspected, and prompt diagnosis is delayed until further complications occur. Serology and blood cultures should be done in every patient presenting with fever after a stay in endemic countries.
Mots-clé
Adult Aortic Valve Insufficiency/etiology Arthritis, Infectious/etiology Blood/microbiology Brucella/isolation & purification Brucellosis/*complications/drug therapy Cerebrospinal Fluid/microbiology Child Drug Combinations/therapeutic use Endocarditis, Bacterial/etiology Female Heart Valve Prosthesis Humans Male Microbial Sensitivity Tests Middle Aged Sepsis/etiology Streptomycin/therapeutic use Sulfamethoxazole/therapeutic use Synovial Fluid/microbiology Tetracyclines/therapeutic use Trimethoprim/therapeutic use Trimethoprim-Sulfamethoxazole Combination
Pubmed
Web of science
Création de la notice
25/01/2008 18:08
Dernière modification de la notice
03/03/2018 18:49
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