Shear-Wave Elastography Assessments of Quadriceps Stiffness Changes prior to, during and after Prolonged Exercise: A Longitudinal Study during an Extreme Mountain Ultra-Marathon.

Détails

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Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_81C2404F0676
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Shear-Wave Elastography Assessments of Quadriceps Stiffness Changes prior to, during and after Prolonged Exercise: A Longitudinal Study during an Extreme Mountain Ultra-Marathon.
Périodique
PloS one
Auteur(s)
Andonian P., Viallon M., Le Goff C., de Bourguignon C., Tourel C., Morel J., Giardini G., Gergelé L., Millet G.P., Croisille P.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
11
Numéro
8
Pages
e0161855
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
In sports medicine, there is increasing interest in quantifying the elastic properties of skeletal muscle, especially during extreme muscular stimulation, to improve our understanding of the impact of alterations in skeletal muscle stiffness on resulting pain or injuries, as well as the mechanisms underlying the relationships between these parameters. Our main objective was to determine whether real-time shear-wave elastography (SWE) can monitor changes in quadriceps muscle elasticity during an extreme mountain ultra-marathon, a powerful mechanical stress model. Our study involved 50 volunteers participating in an extreme mountain marathon (distance: 330 km, elevation: +24,000 m). Quantitative SWE velocity and shear modulus measurements were performed in most superficial quadriceps muscle heads at the following 4 time points: before the race, halfway through the race, upon finishing the race and after recovery (+48 h). Blood biomarker levels were also measured. A significant decrease in the quadriceps shear modulus was observed upon finishing the race (3.31±0.61 kPa) (p<0.001) compared to baseline (3.56±0.63 kPa), followed by a partial recovery +48 h after the race (3.45±0.6 kPa) (p = 0.002) across all muscle heads, as well as for each of the following three muscle heads: the rectus femoris (p = 0.003), the vastus medialis (p = 0.033) and the vastus lateralis (p = 0.001). Our study is the first to assess changes in muscle stiffness during prolonged extreme physical endurance exercises based on shear modulus measurements using non-invasive SWE. We concluded that decreases in stiffness, which may have resulted from quadriceps overuse in the setting of supra-physiological stress caused by the extreme distance and unique elevation of the race, may have been responsible for the development of inflammation and muscle swelling. SWE may hence represent a promising tool for monitoring physiologic or pathological variations in muscle stiffness and may be useful for diagnosing and monitoring muscle changes.

Mots-clé
Adult, Biomarkers/blood, Elastic Modulus, Elasticity Imaging Techniques/methods, Female, Humans, Longitudinal Studies, Male, Middle Aged, Quadriceps Muscle/diagnostic imaging, Quadriceps Muscle/physiology, Running/physiology, Shear Strength, Stress, Mechanical
Pubmed
Web of science
Création de la notice
01/09/2016 12:13
Dernière modification de la notice
03/03/2018 18:48
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