Nosocomial infections occurring during receipt of circulatory support with the paracorporeal ventricular assist system.

Details

Serval ID
serval:BIB_81A062FAC789
Type
Article: article from journal or magazin.
Collection
Publications
Title
Nosocomial infections occurring during receipt of circulatory support with the paracorporeal ventricular assist system.
Journal
Clinical infectious diseases
Author(s)
Mekontso-Dessap A., Kirsch M., Vermes E., Brun-Buisson C., Loisance D., Houël R.
ISSN
1537-6591 (Electronic)
ISSN-L
1058-4838
Publication state
Published
Issued date
01/12/2002
Peer-reviewed
Oui
Volume
35
Number
11
Pages
1308-1315
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
This retrospective study sought to report the spectrum of infections in a homogenous group of 39 patients who underwent implantation of the Thoratec paracorporeal ventricular assist device system (Thoratec Laboratories) in an emergency setting. Thirty-one of the 39 patients developed a total of 99 nosocomial infections (attack rate, 79.5%; incidence, 4.9 per 100 support-days). The lungs were the most frequently involved site (31.3%), and coagulase-negative Staphylococcus species were the pathogens most frequently isolated (16.2%). Infected patients required more transfusions and chest surgical revisions, as well as a longer duration of mechanical ventilation and a longer stay in the intensive care unit, compared with uninfected patients. Cox regression analysis revealed that chest surgical revision was the only independent risk factor for infection at any site (odds ratio, 2.6; 95% confidence interval, 1.2-5.7). There was no significant effect of infection on heart transplantation rate and overall survival.
Keywords
Adult, Cross Infection/epidemiology, Cross Infection/microbiology, Cross Infection/therapy, Emergency Medical Services, Equipment Contamination, Female, Humans, Intensive Care Units, Male, Odds Ratio, Postoperative Complications/epidemiology, Postoperative Complications/microbiology, Postoperative Complications/therapy, Prostheses and Implants/microbiology, Pseudomonas Infections/epidemiology, Pseudomonas Infections/therapy, Regression Analysis, Retrospective Studies, Risk Factors, Staphylococcal Infections/epidemiology, Staphylococcal Infections/therapy, Treatment Outcome
Pubmed
Web of science
Open Access
Yes
Create date
30/03/2019 17:56
Last modification date
20/08/2019 15:41
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