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Immune response to mouse mammary tumour virus.
Current Opinion in Immunology
Superantigens of mouse mammary tumor virus induce a strong cognate interaction between T cells and B cells. In addition to amplifying the virus-infected B-cell pool, this superantigen-driven interaction leads to the differentiation of virus-specific B cells into plasma cells. Successful interaction between T cells and B cells is required for completion of the viral life cycle.
Animals, B-Lymphocytes/immunology, Lymphocyte Cooperation/immunology, Mammary Tumor Virus, Mouse/immunology, Mice, Minor Lymphocyte Stimulatory Antigens/immunology, Retroviridae Infections/immunology, Superantigens/immunology, T-Lymphocytes/immunology, Tumor Virus Infections/immunology
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