The fixation of locally beneficial alleles in a metapopulation.

Détails

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Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_7F423F041903
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
The fixation of locally beneficial alleles in a metapopulation.
Périodique
Genetics
Auteur(s)
Vuilleumier S., Yearsley J.M., Perrin N.
ISSN
0016-6731[print], 0016-6731[linking]
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
178
Numéro
1
Pages
467-475
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Extinction, recolonization, and local adaptation are common in natural spatially structured populations. Understanding their effect upon genetic variation is important for systems such as genetically modified organism management or avoidance of drug resistance. Theoretical studies on the effect of extinction and recolonization upon genetic variance started appearing in the 1970s, but the role of local adaptation still has no good theoretical basis. Here we develop a model of a haploid species in a metapopulation in which a locally adapted beneficial allele is introduced. We study the effect of different spatial patterns of local adaptation, and different metapopulation dynamics, upon the fixation probability of the beneficial allele. Controlling for the average selection pressure, we find that a small area of positive selection can significantly increase the global probability of fixation. However, local adaptation becomes less important as extinction rate increases. Deme extinction and recolonization have a spatial smoothing effect that effectively reduces spatial variation in fitness.
Mots-clé
Alleles, Genotype, Population Dynamics
Pubmed
Web of science
Création de la notice
24/01/2008 18:53
Dernière modification de la notice
03/03/2018 18:43
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