Detraining effects on the mechanical properties and morphology of rat tibiae

Détails

ID Serval
serval:BIB_7E59371F9E3E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Detraining effects on the mechanical properties and morphology of rat tibiae
Périodique
Bio-Medical Materials and Engineering
Auteur(s)
Fujie  H., Miyagaki  J., Terrier  A., Rakotomanana  L., Leyvraz  P. F., Hayashi  K.
ISSN
0959-2989 (Print)
Statut éditorial
Publié
Date de publication
2004
Volume
14
Numéro
2
Pages
219-33
Notes
Journal Article
Research Support, Non-U.S. Gov't
Résumé
To study bone adaptation to detraining in growing rats, nine weeks-old immature female Wistar rats (n=110) were subjected to treadmill running programs (30 or 60 minutes-a-day) for up to 15 weeks, followed by unrestricted cage activities for the subsequent 15 weeks. The results revealed that (1) the cross-sectional area and mechanical properties of the midshaft bone significantly increased in response to running exercise, (2) its structural properties remained unchanged after the cessation of exercise, whereas the material properties returned to control level at a relatively early stage, (3) in the metaphysis, cortical bone area remained unchanged but trabecular bone area decreased in response to running exercise, (4) both areas slightly increased after the cessation of exercise, and (5) the changes in the mechanical properties and morphology of bone depended upon the repetition number and/or the duration of exercise, and were larger with longer duration of exercise.
Mots-clé
Adaptation, Physiological/physiology Anatomy, Cross-Sectional/*methods Animals Body Weight/physiology Bone Development/*physiology Compressive Strength/physiology Female Hardness Motor Activity/*physiology Physical Conditioning, Animal/*methods Rats Rats, Wistar Tibia/*physiology/*radiography
Pubmed
Web of science
Création de la notice
28/01/2008 13:22
Dernière modification de la notice
03/03/2018 18:41
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