Asking about adherence - from flipping the coin to strong evidence.

Détails

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Etat: Serval
Version: Final published version
ID Serval
serval:BIB_7C6ACAF4C15A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Asking about adherence - from flipping the coin to strong evidence.
Périodique
Swiss Medical Weekly
Auteur(s)
Glass T., Cavassini M.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
144
Pages
w14016
Langue
anglais
Notes
Publication types: Journal Article Publication Status: epublish
Résumé
In the era of antiretroviral therapy (ART) as prevention for transmission of HIV as well as treatment for HIV-positive individuals irrespective of CD4 cell counts, the importance of adherence has grown. Although adherence is not the only determinant of treatment success, it is one of the only modifiable risk factors. Treatment failure reduces future treatment options and therefore long-term clinical success as well as increases the possibility of developing drug resistant mutations. Drug-resistant strains of HIV can then be transmitted to uninfected or drug-naïve individuals limiting their future treatment options, making adherence an important public-health topic, especially in resource-limited settings. Adherence should be monitored as a part of routine clinical care; however, no gold standard for assessment of adherence exists. For use in daily clinical practice, self-report is the most likely candidate for widespread use due to its many advantages over other measurement methods, such as low cost and ease of administration. Asking individuals about their adherence behaviour has been shown to yield valid and predictive data - well beyond the mere flip of a coin. However, there is still work to be done. This article reviews the literature and evidence on self-reported adherence, identifies gaps in adherence research, and makes recommendations for clinicians on how to best utilise self-reported adherence data to support patients in daily clinical practice.
Pubmed
Web of science
Open Access
Oui
Création de la notice
13/11/2014 19:29
Dernière modification de la notice
08/05/2019 20:53
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