Muscle fatigue: from observations in humans to underlying mechanisms studied in intact single muscle fibres.

Détails

ID Serval
serval:BIB_7B83270D728E
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Muscle fatigue: from observations in humans to underlying mechanisms studied in intact single muscle fibres.
Périodique
European Journal of Applied Physiology
Auteur(s)
Place N., Yamada T., Bruton J.D., Westerblad H.
ISSN
1439-6327 (Electronic)
ISSN-L
1439-6319
Statut éditorial
Publié
Date de publication
2010
Volume
110
Numéro
1
Pages
1-15
Langue
anglais
Résumé
Prolonged dynamic exercise and sustained isometric contractions induce muscle fatigue, as manifested by decreased performance and a reduction in the maximum voluntary contraction force. Studies with non-invasive measurements in exercising humans show that mechanisms located beyond the sarcolemma are important in the fatigue process. In this review, we describe probable cellular mechanisms underlying fatigue-induced changes in excitation-contraction (E-C) coupling occurring in human muscle fibres during strenuous exercise. We use fatigue-induced changes observed in intact single muscle fibres, where force and cellular Ca(2+) handling can be directly measured, to explain changes in E-C coupling observed in human muscle during exercise.
Mots-clé
Excitation Contraction Coupling, Humans, Isometric Contraction, Muscle Fatigue, Muscle Fibers, Skeletal/metabolism, Muscle Fibers, Skeletal/physiology, Muscle Strength, Muscle, Skeletal/innervation, Muscle, Skeletal/metabolism, Recovery of Function, Time Factors
Pubmed
Web of science
Création de la notice
19/09/2013 9:40
Dernière modification de la notice
03/03/2018 18:35
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