Value of cardiophrenic angle lymph node for the diagnosis of colorectal peritoneal carcinomatosis

Détails

ID Serval
serval:BIB_7AF32D1BB5D1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Value of cardiophrenic angle lymph node for the diagnosis of colorectal peritoneal carcinomatosis
Périodique
Eur J Cancer
Auteur(s)
Caramella C., Pottier E., Borget I., Malka D., Goere D., Boige V., Honore C., Dartigues P., Dumont F., Ducreux M., Elias D., Dromain C.
ISSN-L
1879-0852 (Electronic)0959-8049 (Linking)
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
49
Numéro
18
Pages
3798-805
Langue
anglais
Notes
Caramella, CPottier, EBorget, IMalka, DGoere, DBoige, VHonore, CDartigues, PDumont, FDucreux, MElias, DDromain, CengEnglandOxford, England : 19902013/08/01 06:00Eur J Cancer. 2013 Dec;49(18):3798-805. doi: 10.1016/j.ejca.2013.06.044. Epub 2013 Jul 27.
Résumé
BACKGROUND: Cardiophrenic angle lymph nodes (CPALN) have been reported in patients with abdominopelvic malignancies. We aimed to assess whether the presence of CPALN is associated with peritoneal carcinomatosis (PC) in colorectal cancer. PATIENTS AND METHODS: Between 2007 and 2011, 550 patients with colorectal cancer, including 165 (30%) with PC, had undergone surgery with complete peritoneal exploration. We retrospectively reviewed preoperative CT scans for the presence of CPALN and assessed its association with confirmed PC by univariate and multivariate analyses. RESULTS: CPALN were present in 123 (75%) patients with PC, but absent in 263 (68%) patients without PC (Se: 0.72; Sp: 0.68; PPV: 0.49; NPV: 0.85; [OR], 3.3; p<0.001). PC was the only factor independently associated with CPALN in the multivariate analysis. CPALN was not correlated with the presence of liver metastases. 99 of the 165 patients with PC (62%) had visible signs of PC on CT scan. Among the remaining 66 patients, CPALN were the only potential sign of PC in 41 (62%), (Se 0.62, Sp 0.68, PPV 0.24, and NPV 0.92). CONCLUSION: The detection of CPALN on CT may be of valuable help for the diagnosis of PC in patients with CRC.
Mots-clé
Adult, Aged, Aged, 80 and over, Colorectal Neoplasms/*pathology, Diaphragm, Female, Humans, Logistic Models, Lymph Nodes/*pathology, Lymphatic Metastasis, Male, Middle Aged, Multivariate Analysis, Pericardium, Peritoneal Neoplasms/*diagnosis/*secondary, Peritoneum/radiography, Prognosis, Retrospective Studies, Sensitivity and Specificity, Tomography, X-Ray Computed, Young Adult
Création de la notice
16/09/2016 11:13
Dernière modification de la notice
03/03/2018 18:34
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