Neural control of vascular reactions: impact of emotion and attention.

Détails

Ressource 1Télécharger: 4251.full.pdf (747.96 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_7A813F66B2F6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Neural control of vascular reactions: impact of emotion and attention.
Périodique
Journal of Neuroscience
Auteur(s)
Okon-Singer H., Mehnert J., Hoyer J., Hellrung L., Schaare H.L., Dukart J., Villringer A.
ISSN
1529-2401 (Electronic)
ISSN-L
0270-6474
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
34
Numéro
12
Pages
4251-4259
Langue
anglais
Notes
Publication types: Journal Article
Résumé
This study investigated the neural regions involved in blood pressure reactions to negative stimuli and their possible modulation by attention. Twenty-four healthy human subjects (11 females; age = 24.75 ± 2.49 years) participated in an affective perceptual load task that manipulated attention to negative/neutral distractor pictures. fMRI data were collected simultaneously with continuous recording of peripheral arterial blood pressure. A parametric modulation analysis examined the impact of attention and emotion on the relation between neural activation and blood pressure reactivity during the task. When attention was available for processing the distractor pictures, negative pictures resulted in behavioral interference, neural activation in brain regions previously related to emotion, a transient decrease of blood pressure, and a positive correlation between blood pressure response and activation in a network including prefrontal and parietal regions, the amygdala, caudate, and mid-brain. These effects were modulated by attention; behavioral and neural responses to highly negative distractor pictures (compared with neutral pictures) were smaller or diminished, as was the negative blood pressure response when the central task involved high perceptual load. Furthermore, comparing high and low load revealed enhanced activation in frontoparietal regions implicated in attention control. Our results fit theories emphasizing the role of attention in the control of behavioral and neural reactions to irrelevant emotional distracting information. Our findings furthermore extend the function of attention to the control of autonomous reactions associated with negative emotions by showing altered blood pressure reactions to emotional stimuli, the latter being of potential clinical relevance.
Pubmed
Web of science
Open Access
Oui
Création de la notice
01/05/2014 19:00
Dernière modification de la notice
08/05/2019 20:47
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