Article: article from journal or magazin.
Combined surgery and postoperative radiation therapy for advanced laryngeal and hypopharyngeal carcinomas
International Journal of Radiation Oncology, Biology, Physics
Journal Article --- Old month value: Mar
The survival, pattern of failure and complications in 47 patients with Stage III and IV cancers of the glottis, supraglottis and hypopharynx treated with surgery and postoperative radiotherapy using a new treatment technique referred to as "mini-mantle" were analyzed. The absolute survival probability of the entire group was 53 and 31% at 3 and 5 years. The local control probability at 3 and 5 years was 63 and 58%, and was higher for the supraglottic/hypopharyngeal than for glottic carcinomas. Advanced lesions, lymph node metastases and positive resection margins were significantly related to a worse local control. Five patients developed complications requiring surgical correction, but none experienced mortality. Moderate complications were treated conservatively without lasting sequelae. This technique is a reasonably safe and efficient procedure and can be effectively employed for the management of advanced laryngeal and hypopharyngeal carcinomas after definitive surgery.
Aged Carcinoma, Squamous Cell/radiotherapy/*surgery Combined Modality Therapy Female Humans Hypopharyngeal Neoplasms/radiotherapy/*surgery Laryngeal Neoplasms/radiotherapy/*surgery Male Middle Aged Pharyngeal Neoplasms/*surgery Prognosis
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