Combined surgery and postoperative radiation therapy for advanced laryngeal and hypopharyngeal carcinomas

Détails

ID Serval
serval:BIB_7A6B742365E6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Combined surgery and postoperative radiation therapy for advanced laryngeal and hypopharyngeal carcinomas
Périodique
International Journal of Radiation Oncology, Biology, Physics
Auteur(s)
Mirimanoff  R. O., Wang  C. C., Doppke  K. P.
ISSN
0360-3016 (Print)
Statut éditorial
Publié
Date de publication
03/1985
Volume
11
Numéro
3
Pages
499-504
Notes
Journal Article --- Old month value: Mar
Résumé
The survival, pattern of failure and complications in 47 patients with Stage III and IV cancers of the glottis, supraglottis and hypopharynx treated with surgery and postoperative radiotherapy using a new treatment technique referred to as "mini-mantle" were analyzed. The absolute survival probability of the entire group was 53 and 31% at 3 and 5 years. The local control probability at 3 and 5 years was 63 and 58%, and was higher for the supraglottic/hypopharyngeal than for glottic carcinomas. Advanced lesions, lymph node metastases and positive resection margins were significantly related to a worse local control. Five patients developed complications requiring surgical correction, but none experienced mortality. Moderate complications were treated conservatively without lasting sequelae. This technique is a reasonably safe and efficient procedure and can be effectively employed for the management of advanced laryngeal and hypopharyngeal carcinomas after definitive surgery.
Mots-clé
Aged Carcinoma, Squamous Cell/radiotherapy/*surgery Combined Modality Therapy Female Humans Hypopharyngeal Neoplasms/radiotherapy/*surgery Laryngeal Neoplasms/radiotherapy/*surgery Male Middle Aged Pharyngeal Neoplasms/*surgery Prognosis
Pubmed
Web of science
Création de la notice
24/01/2008 18:12
Dernière modification de la notice
03/03/2018 18:33
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