New perspectives on lamellar keratoplasty.

Details

Serval ID
serval:BIB_7A34B712E91C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
New perspectives on lamellar keratoplasty.
Journal
Advances in therapy
Author(s)
Kymionis G.D., Mikropoulos D.G., Portaliou D.M., Boboridis K.G., Voudouragkaki I.C., Dragoumis N.D., Konstas A.G.
ISSN
1865-8652 (Electronic)
ISSN-L
0741-238X
Publication state
Published
Issued date
05/2014
Peer-reviewed
Oui
Volume
31
Number
5
Pages
494-511
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Lamellar (anterior and posterior) keratoplasty entails the surgical replacement of diseased-only corneal tissue, while healthy host corneal tissue is preserved. Selective keratoplasty offers several advantages in comparison to penetrating keratoplasty such as a lower rate of graft rejection, less endothelial cell loss, faster/superior visual rehabilitation and enhanced resistance to closed injury. The surgical approach of "partial corneal transplantation" may be divided into anterior and posterior: techniques including superficial and deep anterior lamellar keratoplasty (SALK and DALK, respectively) and endothelial keratoplasty as well as Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK). These novel surgical procedures are rapidly becoming the preferred therapy option for specific corneal dysfunctions involving the corneal stroma (SALK, DALK), or corneal endothelium (DSAEK, DMEK). During the past decade, the continuing advancement of surgical techniques and the development of innovative surgical instruments have significantly enhanced corneal transplantation. Lamellar keratoplasty techniques facilitate corneal surgery, provide patients with superior outcomes and can successfully restore vision in corneal-related blindness. Nevertheless, more long-term evidence is needed to better evaluate these promising new techniques.
Keywords
Cornea/pathology, Cornea/surgery, Corneal Diseases/diagnosis, Corneal Diseases/pathology, Corneal Diseases/surgery, Corneal Transplantation/adverse effects, Corneal Transplantation/methods, Corneal Transplantation/trends, Endothelium, Corneal/transplantation, Graft Rejection/prevention & control, Humans, Inventions, Organ Sparing Treatments
Pubmed
Web of science
Create date
30/09/2019 17:22
Last modification date
06/10/2019 6:26
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