PPAR Gamma Receptor, Skin Lipids and Hair

Détails

ID Serval
serval:BIB_79F7130F6D83
Type
Partie de livre
Sous-type
Chapitre: chapitre ou section
Collection
Publications
Titre
PPAR Gamma Receptor, Skin Lipids and Hair
Titre du livre
Lipids and skin health
Auteur(s)
Toffoli B., Desvergne B.
Editeur
Springer
Lieu d'édition
New York
ISBN
978-3-319-09942-2
Statut éditorial
Publié
Date de publication
2015
Editeur scientifique
Pappas A.
Numéro de chapitre
18
Pages
277-288
Langue
anglais
Résumé
Peroxisome proliferator-activated receptors (PPARs) are ligand activated transcription factors belonging to the nuclear hormone receptor superfamily.
PPARγ is involved in many different activities in the epidermis, such as keratinocyte differentiation, permeability barrier recovery, dermal wound closure, sebaceous gland formation, sebocyte differentiation, and melanogenesis.
Preclinical studies with PPARγ ligands on various skin diseases have been performed and they could represent a new strategy in the treatment of scarring alopecia.
PPARγ deserves further studies as therapeutic target, likely not with the current drugs, but with future new classes of safer molecules and in combined therapies.
Création de la notice
28/07/2015 14:22
Dernière modification de la notice
03/03/2018 18:32
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