Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

Détails

ID Serval
serval:BIB_79EC8F8AC91D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
Périodique
Cell death and differentiation
Auteur(s)
Kroemer G., Galluzzi L., Vandenabeele P., Abrams J., Alnemri E. S., Baehrecke E. H., Blagosklonny M. V., El-Deiry W. S., Golstein P., Green D. R., Hengartner M., Knight R. A., Kumar S., Lipton S. A., Malorni W., Nunez G., Peter M. E., Tschopp J., Yuan J., Piacentini M., Zhivotovsky B., Melino G.
ISSN
1350-9047
Statut éditorial
Publié
Date de publication
2009
Peer-reviewed
Oui
Volume
16
Numéro
1
Pages
3-11
Langue
anglais
Résumé
Different types of cell death are often defined by morphological criteria, without a clear reference to precise biochemical mechanisms. The Nomenclature Committee on Cell Death (NCCD) proposes unified criteria for the definition of cell death and of its different morphologies, while formulating several caveats against the misuse of words and concepts that slow down progress in the area of cell death research. Authors, reviewers and editors of scientific periodicals are invited to abandon expressions like 'percentage apoptosis' and to replace them with more accurate descriptions of the biochemical and cellular parameters that are actually measured. Moreover, at the present stage, it should be accepted that caspase-independent mechanisms can cooperate with (or substitute for) caspases in the execution of lethal signaling pathways and that 'autophagic cell death' is a type of cell death occurring together with (but not necessarily by) autophagic vacuolization. This study details the 2009 recommendations of the NCCD on the use of cell death-related terminology including 'entosis', 'mitotic catastrophe', 'necrosis', 'necroptosis' and 'pyroptosis'.
Mots-clé
apoptosis, autophagy, comification, excitotoxicity, necrosis, Wallerian degeneration, MITOCHONDRIAL-MEMBRANE PERMEABILIZATION, MITOTIC CATASTROPHE, MOLECULAR-MECHANISMS, CASPASE-1 ACTIVATION, INDUCED APOPTOSIS, VITAL FUNCTIONS, TUMOR-CELLS, IN-VIVO, AUTOPHAGY, NECROSIS
Web of science
Open Access
Oui
Création de la notice
03/12/2009 10:39
Dernière modification de la notice
08/05/2019 20:44
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