Épidémiologie, populations à risque et phénotypes cliniques du syndrome d’apnées du sommeil [Epidemiology, risk factors and phenotypes of sleep breathing disorders]

Détails

ID Serval
serval:BIB_796E1CFBB570
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Épidémiologie, populations à risque et phénotypes cliniques du syndrome d’apnées du sommeil [Epidemiology, risk factors and phenotypes of sleep breathing disorders]
Périodique
Presse medicale
Auteur(s)
Heinzer R.
ISSN
2213-0276 (Electronic)
ISSN-L
0755-4982
Statut éditorial
Publié
Date de publication
04/2017
Peer-reviewed
Oui
Volume
46
Numéro
4
Pages
388-394
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Recent epidemiological studies show that the prevalence of sleep-disordered breathing seems to be higher than previously estimated in the middle to older aged general population with approximatively 49% of men and 23% of women being affected. This higher than expected prevalence of sleep-disordered breathing seems to be due to the high sensitivity of current recording techniques and to the new and more inclusive definition of respiratory events (hypopnea definition in particular). Male sex, age, and truncal obesity (large neck girth, high waist to hip ratio) are the main risk factors for sleep-disordered breathing. Among sleep-disordered breathing patients, different phenotypes can be observed according to the underlying pathophysiologic mechanism of their condition : purely anatomical impairment, central breathing control instability (high "loop gain"), low arousal threshold, or sleep-associated pharyngeal muscles dysfunction. A better phenotyping of the patients could help directing the treatment to the specific cause of their disorder.

Mots-clé
Age Factors, Female, Humans, Male, Obesity, Abdominal/complications, Risk Factors, Sex Factors, Sleep Apnea Syndromes/epidemiology, Sleep Apnea Syndromes/etiology, Sleep Apnea Syndromes/therapy
Pubmed
Web of science
Création de la notice
22/12/2016 10:20
Dernière modification de la notice
20/08/2019 15:35
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