Teratogenic and toxic effects of alcohol ethoxylate and alcohol ethoxy sulfate surfactants on Xenopus laevis embryos and tadpoles.

Détails

ID Serval
serval:BIB_77F2199FE396
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Teratogenic and toxic effects of alcohol ethoxylate and alcohol ethoxy sulfate surfactants on Xenopus laevis embryos and tadpoles.
Périodique
Ecotoxicology and Environmental Safety
Auteur(s)
Cardellini P., Ometto L.
ISSN
0147-6513 (Print)
ISSN-L
0147-6513
Statut éditorial
Publié
Date de publication
2001
Peer-reviewed
Oui
Volume
48
Numéro
2
Pages
170-177
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
The two surfactants tested, an alcohol ethoxylate (AE) and an alcohol ethoxy sulfate (AES), demonstrate both teratogenic and toxic effects in Xenopus laevis embryos and tadpoles. From acute tests and observations of malformations under light and electron microscopy, the AES produced less teratogenic and toxic effects than the AE, from which it differs only by the presence of a sulfate in the hydrophilic group of the molecule. The 72-h LC(50) was 4.59 mg/L for the AE and 6.75 g/L for the AES. The tissues most affected were the epithelia, particularly of the gills. As the AE exhibited ultrastructural alterations of mitochondria and narcotic effects, O(2) consumption was studied in treated tadpoles; results indicated collapse of the electrochemical gradient in mitochondria.
Mots-clé
Abnormalities, Drug-Induced/pathology, Alcohols/toxicity, Animals, Embryo, Nonmammalian/drug effects, Embryonic Development, Gills/pathology, Larva/drug effects, Larva/growth & development, Microscopy, Electron, Scanning, Morphogenesis/drug effects, Oxygen Consumption/drug effects, Sulfuric Acid Esters/toxicity, Surface-Active Agents/toxicity, Survival Rate, Teratogens/toxicity, Xenopus laevis
Pubmed
Web of science
Création de la notice
19/11/2007 11:34
Dernière modification de la notice
03/03/2018 18:28
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