Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Thérapies inhalées dans la mucoviscidose [Inhaled therapies for cystic fibrosis].
Revue Médicale Suisse
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Inhaled therapies play a significant role in the management of cystic fibrosis patients. Mucolytic and airway-rehydrating agents improve mucociliary clearance and respiratory functional status. Nebulized antibiotherapy achieve high local concentration, while reducing systemic toxicity. Tolerance to inhaled treatments is good excepting frequent bronchoconstriction which can usually be prevented by prior administration of beta2-mimetics. The majority of treatments are only available in liquid formulations. Thus, nebulization is the most frequently used inhalation mode. Vibrating-mesh nebulizers have significantly reduced inhalation time.
Administration, Inhalation, Anti-Bacterial Agents/administration & dosage, Anti-Inflammatory Agents/administration & dosage, Bronchodilator Agents/administration & dosage, Cystic Fibrosis/drug therapy, Cystic Fibrosis/therapy, Deoxyribonuclease I/administration & dosage, Humans, Mucociliary Clearance/drug effects, Nebulizers and Vaporizers, Respiratory Therapy/methods, Respiratory Therapy/trends, Saline Solution, Hypertonic/administration & dosage
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