Acquired aphasia, dementia, and behavior disorder with epilepsy and continuous spike and waves during sleep in a child

Details

Serval ID
serval:BIB_76BDC9F3F820
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Acquired aphasia, dementia, and behavior disorder with epilepsy and continuous spike and waves during sleep in a child
Journal
Epilepsia
Author(s)
Roulet  E., Deonna  T., Gaillard  F., Peter-Favre  C., Despland  P. A.
ISSN
0013-9580 (Print)
Publication state
Published
Issued date
08/1991
Volume
32
Number
4
Pages
495-503
Notes
Case Reports
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jul-Aug
Abstract
Severe persistent neuropsychological disorders sometimes develop in the course of a focal epilepsy of unknown origin in previously normal children. Very frequent bilateral focal or generalized discharges are often noted on the sleep EEG records of these patients with no evidence of clinical seizures. The relation between these paroxysms and the observed deterioration remains unclear. We report a child with a partial complex epilepsy and severe disturbances of language, cognition, and behavior acquired in the early years of development who was followed for 15 years. A correlation between the evolution of the striking EEG abnormalities during sleep and the neuropsychological disorders could be established retrospectively. The observed sequence of onset and recovery of the aphasia, the dementia, and the "psychotic" behavior makes a direct causal relation between the deficits quite unlikely. Rather it suggests an association of independent symptoms with a specific language disorder becoming manifest in the course of the evolution. This child shows many of the main characteristics of the syndromes of "acquired aphasia with convulsive disorder" (Landau-Kleffner syndrome) and "epilepsy with continuous spike waves during sleep." Both syndromes describe probably different facets of a similar underlying, still unexplained cerebral dysfunction.
Keywords
Adolescent Aphasia/*physiopathology Child Child Behavior Disorders/*physiopathology Child, Preschool Dementia/*physiopathology Developmental Disabilities/physiopathology *Electroencephalography Epilepsy/*physiopathology Epilepsy, Temporal Lobe/physiopathology Humans Language Disorders/physiopathology Longitudinal Studies Male Prognosis Retrospective Studies Sleep/*physiology Syndrome
Pubmed
Web of science
Create date
25/01/2008 12:40
Last modification date
20/08/2019 15:33
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