Budesonide in the treatment of collagenous colitis

Détails

ID Serval
serval:BIB_7653406CD834
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Budesonide in the treatment of collagenous colitis
Périodique
Digestion
Auteur(s)
Delarive  J., Saraga  E., Dorta  G., Blum  A.
ISSN
0012-2823 (Print)
Statut éditorial
Publié
Date de publication
08/1998
Volume
59
Numéro
4
Pages
364-6
Notes
Clinical Trial
Journal Article --- Old month value: Jul-Aug
Résumé
Collagenous colitis is characterized by watery diarrhea and inflammatory infiltration associated with a subepithelial collagen deposit on colonic biopsies despite a normal or subnormal endoscopic appearance. We here describe 5 patients treated with the locally active steroid budesonide. Complete and partial response was observed in 3 and 2 patients, respectively. Budesonide thus seems to be of therapeutic benefit in collagenous colitis. Prospective randomized long-term studies are needed to support this hypothesis.
Mots-clé
Adult Aged Aged, 80 and over Anti-Inflammatory Agents/*therapeutic use Biopsy Budesonide/*therapeutic use Colitis/complications/*drug therapy/pathology Collagen/*metabolism Collagen Diseases/complications/*drug therapy/pathology Colon/metabolism/pathology Colonoscopy Female Follow-Up Studies Humans Male Middle Aged
Pubmed
Web of science
Création de la notice
25/01/2008 16:48
Dernière modification de la notice
03/03/2018 18:25
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