A user's guide to the encyclopedia of DNA elements (ENCODE).
Details
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_7651C0505F00
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A user's guide to the encyclopedia of DNA elements (ENCODE).
Journal
PLoS biology
Working group(s)
ENCODE Project Consortium
Contributor(s)
Stamatoyannopoulos J., Snyder M., Dunham I., Hardison R.C., Bernstein B.E., Gingeras T.R., Kent W.J., Birney E., Wold B., Crawford G.E., Bernstein B.E., Epstein C.B., Shoresh N., Ernst J., Mikkelsen T.S., Kheradpour P., Zhang X., Wang L., Issner R., Coyne M.J., Durham T., Ku M., Truong T., Ward L.D., Altshuler R.C., Lin M.F., Kellis M., Gingeras T.R., Davis C.A., Kapranov P., Dobin A., Zaleski C., Schlesinger F., Batut P., Chakrabortty S., Jha S., Lin W., Drenkow J., Wang H., Bell K., Gao H., Bell I., Dumais E., Dumais J., Antonarakis S.E., Ucla C., Borel C., Guigo R., Djebali S., Lagarde J., Kingswood C., Ribeca P., Sammeth M., Alioto T., Merkel A., Tilgner H., Carninci P., Hayashizaki Y., Lassmann T., Takahashi H., Abdelhamid R.F., Hannon G., Fejes-Toth K., Preall J., Gordon A., Sotirova V., Reymond A., Howald C., Graison E., Chrast J., Ruan Y., Ruan X., Shahab A., Ting Poh W., Wei C.L., Crawford G.E., Furey T.S., Boyle A.P., Sheffield N.C., Song L., Shibata Y., Vales T., Winter D., Zhang Z., London D., Wang T., Birney E., Keefe D., Iyer V.R., Lee B.K., McDaniell R.M., Liu Z., Battenhouse A., Bhinge A.A., Lieb J.D., Grasfeder L.L., Showers K.A., Giresi P.G., Kim S.K., Shestak C., Myers R.M., Pauli F., Reddy T.E., Gertz J., Partridge E.C., Jain P., Sprouse R.O., Bansal A., Pusey B., Muratet M.A., Varley K.E., Bowling K.M., Newberry K.M., Nesmith A.S., Dilocker J.A., Parker S.L., Waite L.L., Thibeault K., Roberts K., Absher D.M., Wold B., Mortazavi A., Williams B., Marinov G., Trout D., Pepke S., King B., McCue K., Kirilusha A., DeSalvo G., Fisher-Aylor K., Amrhein H., Vielmetter J., Sherlock G., Sidow A., Batzoglou S., Rauch R., Kundaje A., Libbrecht M., Margulies E.H., Parker S.C., Elnitski L., Green E.D., Hubbard T., Harrow J., Searle S., Kokocinski F., Aken B., Frankish A., Hunt T., Despacio-Reyes G., Kay M., Mukherjee G., Bignell A., Saunders G., Boychenko V., Van Baren M., Brown R.H., Khurana E., Balasubramanian S., Zhang Z., Lam H., Cayting P., Robilotto R., Lu Z., Guigo R., Derrien T., Tanzer A., Knowles D.G., Mariotti M., James Kent W., Haussler D., Harte R., Diekhans M., Kellis M., Lin M., Kheradpour P., Ernst J., Reymond A., Howald C., Graison E.A., Chrast J., Tress M., Rodriguez J.M., Snyder M., Landt S.G., Raha D., Shi M., Euskirchen G., Grubert F., Kasowski M., Lian J., Cayting P., Lacroute P., Xu Y., Monahan H., Patacsil D., Slifer T., Yang X., Charos A., Reed B., Wu L., Auerbach R.K., Habegger L., Hariharan M., Rozowsky J., Abyzov A., Weissman S.M., Gerstein M., Struhl K., Lamarre-Vincent N., Lindahl-Allen M., Miotto B., Moqtaderi Z., Fleming J.D., Newburger P., Farnham P.J., Frietze S., O'Geen H., Xu X., Blahnik K.R., Cao A.R., Iyengar S., Stamatoyannopoulos J.A., Kaul R., Thurman R.E., Wang H., Navas P.A., Sandstrom R., Sabo P.J., Weaver M., Canfield T., Lee K., Neph S., Roach V., Reynolds A., Johnson A., Rynes E., Giste E., Vong S., Neri J., Frum T., Johnson E.M., Nguyen E.D., Ebersol A.K., Sanchez M.E., Sheffer H.H., Lotakis D., Haugen E., Humbert R., Kutyavin T., Shafer T., Dekker J., Lajoie B.R., Sanyal A., James Kent W., Rosenbloom K.R., Dreszer T.R., Raney B.J., Barber G.P., Meyer L.R., Sloan C.A., Malladi V.S., Cline M.S., Learned K., Swing V.K., Zweig A.S., Rhead B., Fujita P.A., Roskin K., Karolchik D., Kuhn R.M., Haussler D., Birney E., Dunham I., Wilder S.P., Keefe D., Sobral D., Herrero J., Beal K., Lukk M., Brazma A., Vaquerizas J.M., Luscombe N.M., Bickel P.J., Boley N., Brown J.B., Li Q., Huang H., Gerstein M., Habegger L., Sboner A., Rozowsky J., Auerbach R.K., Yip K.Y., Cheng C., Yan K.K., Bhardwaj N., Wang J., Lochovsky L., Jee J., Gibson T., Leng J., Du J., Hardison R.C., Harris R.S., Song G., Miller W., Haussler D., Roskin K., Suh B., Wang T., Paten B., Noble W.S., Hoffman M.M., Buske O.J., Weng Z., Dong X., Wang J., Xi H., Tenenbaum S.A., Doyle F., Penalva L.O., Chittur S., Tullius T.D., Parker S.C., White K.P., Karmakar S., Victorsen A., Jameel N., Bild N., Grossman R.L., Snyder M., Landt S.G., Yang X., Patacsil D., Slifer T., Dekker J., Lajoie B.R., Sanyal A., Weng Z., Whitfield T.W., Wang J., Collins P.J., Trinklein N.D., Partridge E.C., Myers R.M., Giddings M.C., Chen X., Khatun J., Maier C., Yu Y., Gunawardena H., Risk B., Feingold E.A., Lowdon R.F., Dillon L.A., Good P.J., Harrow J., Searle S.
ISSN
1545-7885 (Electronic)
ISSN-L
1544-9173
Publication state
Published
Issued date
04/2011
Peer-reviewed
Oui
Volume
9
Number
4
Pages
e1001046
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural
Publication Status: ppublish
Publication Status: ppublish
Abstract
The mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the scientific and medical communities to interpret the human genome sequence and apply it to understand human biology and improve health. The ENCODE Consortium is integrating multiple technologies and approaches in a collective effort to discover and define the functional elements encoded in the human genome, including genes, transcripts, and transcriptional regulatory regions, together with their attendant chromatin states and DNA methylation patterns. In the process, standards to ensure high-quality data have been implemented, and novel algorithms have been developed to facilitate analysis. Data and derived results are made available through a freely accessible database. Here we provide an overview of the project and the resources it is generating and illustrate the application of ENCODE data to interpret the human genome.
Keywords
Base Sequence, Chromatin/metabolism, Conserved Sequence, DNA Methylation, DNA-Binding Proteins/genetics, DNA-Binding Proteins/metabolism, Databases, Nucleic Acid, Gene Components, Gene Expression Regulation, Genome, Human, Humans, Internet, Models, Genetic, Quality Control, RNA, Messenger/genetics, RNA-Binding Proteins/genetics, RNA-Binding Proteins/metabolism
Pubmed
Web of science
Open Access
Yes
Create date
17/01/2012 13:00
Last modification date
09/08/2024 15:01
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