Image acquisition for intravoxel incoherent motion imaging of kidneys should be triggered at the instant of maximum blood velocity: evidence obtained with simulations and in vivo experiments.

Détails

ID Serval
serval:BIB_74D530C8D467
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Image acquisition for intravoxel incoherent motion imaging of kidneys should be triggered at the instant of maximum blood velocity: evidence obtained with simulations and in vivo experiments.
Périodique
Magnetic resonance in medicine
Auteur(s)
Milani B., Ledoux J.B., Rotzinger D.C., Kanemitsu M., Vallée J.P., Burnier M., Pruijm M.
ISSN
1522-2594 (Electronic)
ISSN-L
0740-3194
Statut éditorial
Publié
Date de publication
01/2019
Peer-reviewed
Oui
Volume
81
Numéro
1
Pages
583-593
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
To demonstrate that diffusion-weighted images should be acquired at the instant of maximum blood velocity in kidneys to extract the perfusion fraction (PF) by the bi-exponential intravoxel incoherent motion model.
The PF values were measured in Monte-Carlo simulations corresponding to different blood velocities with a constant known PF. The distribution of the measured PF values (PF-distribution) was characterized quantitatively by 3 markers highlighting the deviation of the measurement from the true PF. Diffusion-weighted images of kidneys were acquired in 10 healthy volunteers at the instant of maximal respectively minimal blood velocity in the renal artery (V <sub>max</sub> versus V <sub>min</sub> acquisition). The PF-distributions measured from the V <sub>max</sub> and V <sub>min</sub> acquisitions were compared mutually and with simulated PF-distributions using the 3 markers. A radiologist evaluated the quality of the PF maps.
The PF-distributions measured in the simulations were spread around the true PF value, and spreading was reduced as blood velocity increased. A comparison between simulated and in vivo PF-distributions suggests that a similar phenomenon is plausible in vivo. The quality of the PF maps of the V <sub>max</sub> -acquisition was scored higher by the radiologist than those of the V <sub>min</sub> -acquisition in 95% of cases (19 of 20).
The PF maps are of better quality when the V <sub>max</sub> -acquisition is used. We show evidence supporting the hypothesis that the variation of PF along the cardiac cycle is due to oscillations between a poor estimation when the blood velocity is low, and a better estimation when blood velocity is higher.
Mots-clé
IVIM, diffusion, kidneys, perfusion
Pubmed
Web of science
Open Access
Oui
Création de la notice
04/09/2018 11:50
Dernière modification de la notice
20/08/2019 15:32
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