Après votre arrêt cardiaque, vous prendrez bien un peu d'élixir de (sur)vie [After your heart arrest, would you like to test a medicinal elixir?].

Détails

ID Serval
serval:BIB_74D0B2079E58
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Après votre arrêt cardiaque, vous prendrez bien un peu d'élixir de (sur)vie [After your heart arrest, would you like to test a medicinal elixir?].
Périodique
Revue Médicale Suisse
Auteur(s)
Carron P.N., Hugli O., Liaudet L., Yersin B.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
2005
Volume
1
Numéro
6
Pages
448-451
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Résumé
So far, cardiac arrest is still associated with high mortality or severe neurological disability in survivors. At the tissue level, cardiac arrest results into an acute condition of generalized hypoxia. A better understanding of the pathophysiology of ischemia-reperfusion and of the inflammatory response that develops after cardiac arrest could help to design novel therapeutic strategies in the future. It seems unlikely that a single drug, acting as a <magic bullet>, might be able to improve survival or neurological prognosis. Lessons learned from pathophysiological mechanisms rather indicate that combined therapies, involving thrombolysis, neuroprotective agents, antioxidants and anti-inflammatory molecules, together with temperature cooling, might represent helpful strategies to improve patient's outcome after cardiac arrest.
Mots-clé
Anti-Inflammatory Agents/therapeutic use, Antioxidants/therapeutic use, Fibrinolytic Agents/therapeutic use, Heart Arrest/prevention & control, Humans, Neuroprotective Agents/therapeutic use
Pubmed
Création de la notice
29/01/2008 9:42
Dernière modification de la notice
03/03/2018 18:22
Données d'usage