Mise à jour sur l'hépatite E [An update on hepatitis E].

Détails

ID Serval
serval:BIB_7488FCBC71F0
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Mise à jour sur l'hépatite E [An update on hepatitis E].
Périodique
Revue Médicale Suisse
Auteur(s)
Hiroz P., Gouttenoire J., Dao Thi V.L., Sahli R., Telenti A., Moradpour D., Doerig C.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
2013
Volume
9
Numéro
396
Pages
1594-1598
Langue
français
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish
Résumé
The hepatitis E virus (HEV) is an RNA virus transmitted via the fecal-oral route or through uncooked animal meat products. Of the 4 known genotypes, genotype 3 is responsible for autochthonous infections in industrialized countries, with a seroprevalence in Switzerland estimated as high as 22%. The majority of infections is asymptomatic but a minority of patients, notably men over 50 or with underlying liver disease, can present with severe acute hepatitis. Chronic hepatitis E with HEV of genotype 3 has been observed in immunosuppressed patients, mostly transplant recipients. Serology is not sufficiently sensitive, especially in immunosuppressed patients, making PCR identification the preferred test for diagnosing active infection. Ribavirin or interferon-alpha can be used to treat chronic hepatitis E if reduction of immunosuppressive treatment does not result in viral elimination.
Mots-clé
Adolescent, Adult, Age Factors, Antiviral Agents/therapeutic use, Female, Genotype, Hepatitis E/epidemiology, Hepatitis E/therapy, Hepatitis E virus/genetics, Hepatitis E virus/isolation & purification, Humans, Immunocompromised Host, Male, Middle Aged, Risk Factors, Seroepidemiologic Studies, Sex Factors, Switzerland/epidemiology, Young Adult
Pubmed
Création de la notice
16/02/2014 12:54
Dernière modification de la notice
20/08/2019 15:32
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