Imaging of the unstable plaque: how far have we got?

Détails

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Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_73ABB4B19DC0
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Imaging of the unstable plaque: how far have we got?
Périodique
European Heart Journal
Auteur(s)
Matter C.M., Stuber M., Nahrendorf M.
ISSN
1522-9645[electronic]
Statut éditorial
Publié
Date de publication
2009
Volume
30
Numéro
21
Pages
2566-2574
Langue
anglais
Résumé
Rupture of unstable plaques may lead to myocardial infarction or stroke and is the leading cause of morbidity and mortality in western countries. Thus, there is a clear need for identifying these vulnerable plaques before the rupture occurs. Atherosclerotic plaques are a challenging imaging target as they are small and move rapidly, especially in the coronary tree. Many of the currently available imaging tools for clinical use still provide minimal information about the biological characteristics of plaques, because they are limited with respect to spatial and temporal resolution. Moreover, many of these imaging tools are invasive. The new generation of imaging modalities such as magnetic resonance imaging, nuclear imaging such as positron emission tomography and single photon emission computed tomography, computed tomography, fluorescence imaging, intravascular ultrasound, and optical coherence tomography offer opportunities to overcome some of these limitations. This review discusses the potential of these techniques for imaging the unstable plaque.
Mots-clé
Atherosclerosis, Molecular imaging, Vulnerable plaque, Coronary-Artery-Disease, Magnetic-Resonance Angiography, Acute Myocardial-Infarction, Ultrasmall Superparamagnetic Particles, Optical Coherence Tomography, Positron-Emission-Tomography, Water Suppression Iron, In-Vivo, Intravascular Ultrasound, Atherosclerotic Plaques
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/11/2009 17:43
Dernière modification de la notice
08/05/2019 20:25
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