Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Adrenal crisis presenting as hypoglycemic coma.
Intensive care medicine
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
An 18-month-old male infant presented with hypoglycemic coma and clinical signs of bronchopneumonia. He was suspected of suffering from septic shock. The patient progressed to irreversible multiple organ failure before the diagnosis of adrenal crisis was established. Plasma levels of ACTH and cortisol remained undetectable. Renin and aldosterone were normal. An autopsy failed to demonstrate any adrenal gland cortical tissue. Immunohistochemical staining demonstrated the presence of all pituitary hormones except ACTH, establishing the diagnosis of isolated ACTH deficiency. Intensive care clinicians should consider adrenal crisis in non-diabetic children with hypoglycemia and rapid circulatory deterioration.
Adrenal Cortex, Adrenocorticotropic Hormone, Coma, Fatal Outcome, Glucose, Humans, Hypoglycemia, Infant, Male
Web of science
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