Hypergonadotropic hypogonadism after ovarian tissue cryopreservation on a 13-year-old female: A case report and review of the literature.
Details
Serval ID
serval:BIB_735D6D4A7CDF
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Hypergonadotropic hypogonadism after ovarian tissue cryopreservation on a 13-year-old female: A case report and review of the literature.
Journal
Journal of gynecology obstetrics and human reproduction
ISSN
2468-7847 (Electronic)
ISSN-L
2468-7847
Publication state
Published
Issued date
02/2021
Peer-reviewed
Oui
Volume
50
Number
2
Pages
102029
Language
english
Notes
Publication types: Case Reports ; Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
Ovarian failure is a major long-term adverse event following gonadotoxic treatment of malignant diseases. Ovarian tissue cryopreservation can be offered in some conditions to preserve fertility. We report the case of a 13-year-old female with a diagnosis of acute myeloid leukemia, who presented with hypergonadotropic hypogonadism after unilateral ovariectomy for fertility preservation and before highly gonadotoxic treatment. Even though damage seemed only partial, this case suggests that the remaining contralateral ovarian function may be compromised after ovarian tissue cryopreservation, leading per se to a hypergonadotropic hypogonadism. Although indication of ovarian cryopreservation is not called into question in situations of highly gonadotoxic therapy, this procedure should only be performed after evaluation by a specialized multidisciplinary team and provided a solid indication.
Keywords
Adolescent, Cryopreservation, Female, Fertility Preservation, Humans, Hypogonadism/etiology, Leukemia, Myeloid, Acute/therapy, Ovariectomy, Fertility preservation, Gonadotoxic treatment, Hypergonadotropic hypogonadism, Oncofertility, Ovarian failure, Ovarian tissue cryopreservation
Pubmed
Web of science
Open Access
Yes
Create date
07/12/2020 14:12
Last modification date
04/06/2024 6:46