Changes in health-related quality of life over a 1-year follow-up period in children with inflammatory bowel disease.

Détails

ID Serval
serval:BIB_734A0BCB54F9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Changes in health-related quality of life over a 1-year follow-up period in children with inflammatory bowel disease.
Périodique
Quality of life research
Auteur(s)
Werner H., Landolt M.A., Buehr P., Koller R., Nydegger A., Spalinger J., Heyland K., Schibli S., Braegger C.P.
Collaborateur(s)
Swiss IBD Cohort Study Group
ISSN
1573-2649 (Electronic)
ISSN-L
0962-9343
Statut éditorial
Publié
Date de publication
06/2017
Peer-reviewed
Oui
Volume
26
Numéro
6
Pages
1617-1626
Langue
anglais
Notes
Publication types: Journal Article ; Multicenter Study
Publication Status: ppublish
Résumé
Little is known about disease-specific health-related quality-of-life (HRQoL) changes over time in paediatric patients with inflammatory bowel disease (IBD), and about their associations with baseline medical characteristics.
In this study, 153 paediatric patients with IBD from the multicentre prospective Swiss IBD cohort study were included at baseline. Of these, 90 patients were analysed at a 1-year follow-up. Medical data were extracted from hospital records, while HRQoL data were measured using the standardized, self-report disease-specific IMPACT-III questionnaire.
The IBD diagnosis of the included children was made an average of 2.0 years before their baseline assessment. Over the 1-year follow-up period, a significant increase in overall HRQoL and in the HRQoL domain 'physical functioning' was evident. On multivariate analysis, overall HRQoL changes over time were predicted by baseline HRQoL, baseline disease activity, and disease activity changes over time. HRQoL improvements were significantly associated with decreases in physician-assessed disease activity. Children reporting a low baseline HRQoL and children with inactive or mildly-active disease experienced greater improvements.
Children with more severe baseline disease activity had the greatest risk for HRQoL deterioration over the 1-year follow-up period. However, among possible factors that might influence HRQoL changes over time, the child's medical characteristics explained only a small proportion of their variability in our sample. We, therefore, recommend that researchers and clinicians focus on factors that are not incorporated within the multidimensional HRQoL concept if they seek to gain better insights into factors that influence HRQoL changes over time in children with IBD.

Mots-clé
Adolescent, Child, Chronic Disease, Cohort Studies, Female, Follow-Up Studies, Humans, Inflammatory Bowel Diseases/psychology, Male, Prospective Studies, Quality of Life/psychology, Surveys and Questionnaires, Time Factors, Children, Chronic disease, Health-related quality of life, Inflammatory bowel disease, Paediatric, Psychological adaptation
Pubmed
Web of science
Création de la notice
21/02/2017 19:19
Dernière modification de la notice
03/03/2018 18:19
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