Endothelial function, mechanical stress and atherosclerosis.

Détails

ID Serval
serval:BIB_733D9457A849
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Endothelial function, mechanical stress and atherosclerosis.
Périodique
Advances in Cardiology
Auteur(s)
Hayoz D., Mazzolai L.
ISSN
0065-2326
Statut éditorial
Publié
Date de publication
2007
Volume
44
Pages
62-75
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Atherosclerosis and its complications represent the leading cause of morbidity and mortality in the industrialized as well as in the developing countries. Classical cardiovascular risk factors have been identified over the past decades leading to recommendations for life style modifications and to the development of efficient and well-tolerated drug regimens aimed at reducing the occurrence of cardiovascular complications. The endothelium due to its position in the circulation is the first organ being exposed to circulating noxious elements and solutes as well as to the mechanical aggressions generated by heartbeats and pulsating blood flow. This review addresses the relevance of the combined effects of the mechanical stress and cardiovascular risk factors on the early phases of atherosclerosis.
Mots-clé
Age Factors, Atherosclerosis/metabolism, Atherosclerosis/physiopathology, Blood Flow Velocity, Blood Pressure, Endothelium, Vascular/metabolism, Endothelium, Vascular/physiopathology, Humans, Nitric Oxide/metabolism, Pulsatile Flow, Risk Factors, Stress, Mechanical, Vascular Resistance
Pubmed
Web of science
Création de la notice
17/01/2008 17:38
Dernière modification de la notice
03/03/2018 18:19
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